A coach leaves Mendoza’s Terminal del Sol before sunrise, climbs the Cristo Redentor tunnel by mid-morning, and drops you in Santiago in time for a late dinner. That single overland crossing is the most famous multi-day option out of Mendoza, but it is far from the only one, and the city’s real strength for longer stays is how many genuinely different trips fan out from it once you stop treating it as a one-day wine stop.